Endocrine Abstracts

Mammalian genome sequencing has driven the development of new -omic technologies that are capable of defining the genes, proteins and biological pathways that mediate cellular responses to endogenous and exogenous stimuli. We have used transcript profiling, which allows the expression levels of thousands of genes to be measured simultaneously, to define the molecular mechanism of 17beta-estradiol (E2) signalling in vivo, using the rodent uterotrophic assay as a model experimen...